2000 "F-D-C" Index of NASDAQ Stocks

2000 Performance Of Biopharmaceutical And Service Stocks Tracked By "F-D-C" Index: High, Low And Close For The Yea

<pre> Pharmaceuticals Company........................ Alkermes (1) 2000 Range 52-Wk High.......... 98.50 2000 Range 52-Wk Low........... 21. 56 2000 Close..................... 31.38 1999 Close..................... 24.56 2000-1999 Net Change Points.... 6.82 2000-1999 Net Change Percent... 27.8% 1999-1998 Net Change Points.... 13.47 1999-1998 Net Change Percent... 121.5% Footnote....................... (1) stock split 2 for 1. Company........................ Affymetrix (1) 2000 Range 52-Wk High.......... 163.50 2000 Range 52-Wk Low........... 42.31 2000 Close..................... 74.44 1999 Close..................... 84.84 2000-1999 Net Change Points.... -10.40 2000-1999 Net Change Percent... -12.3% 1999-1998 Net Change Points.... 72.65 1999-1998 Net Change Percent... 596.0% Footnote....................... (1) stock split 2 for 1. Company........................ Amgen 2000 Range 52-Wk High.......... 80.44 2000 Range 52-Wk Low........... 50.00 2000 Close..................... 63.94 1999 Close..................... 60.06 2000-1999 Net Change Points.... 3.88 2000-1999 Net Change Percent... 6.5% 1999-1998 Net Change Points.... 33.92 1999-1998 Net Change Percent... 129.8% Company........................ Amylin Pharm. 2000 Range 52-Wk High.......... 18.38 2000 Range 52-Wk Low........... 6.50 2000 Close..................... 7.88 1999 Close..................... 8.34 2000-1999 Net Change Points.... -0.46 2000-1999 Net Change Percent... -5.6% 1999-1998 Net Change Points.... 7.84 1999-1998 Net Change Percent... 1568.8% Company........................ AxyS Pharm. 2000 Range 52-Wk High.......... 20.25 2000 Range 52-Wk Low........... 3.53 2000 Close..................... 5.63 1999 Close..................... 4.06 2000-1999 Net Change Points.... 1.57 2000-1999 Net Change Percent... 38.7% 1999-1998 Net Change Points.... -1.82 1999-1998 Net Change Percent... -31.0% Company........................ Biogen 2000 Range 52-Wk High.......... 129.00 2000 Range 52-Wk Low........... 47.13 2000 Close..................... 60.06 1999 Close..................... 84.50 2000-1999 Net Change Points.... -24.44 2000-1999 Net Change Percent... -28.9% 1999-1998 Net Change Points.... 43.00 1999-1998 Net Change Percent... 103.6% Company........................ Bio-Technology General 2000 Range 52-Wk High.......... 21.00 2000 Range 52-Wk Low........... 6.38 2000 Close..................... 7.06 1999 Close..................... 15.25 2000-1999 Net Change Points.... -8.19 2000-1999 Net Change Percent... -53.7% 1999-1998 Net Change Points.... 8.31 1999-1998 Net Change Percent... 119.7% Company........................ Cell Genesys 2000 Range 52-Wk High.......... 61.75 2000 Range 52-Wk Low........... 11.13 2000 Close..................... 22.81 1999 Close..................... 12.81 2000-1999 Net Change Points.... 10.00 2000-1999 Net Change Percent... 78.0% 1999-1998 Net Change Points.... 6.81 1999-1998 Net Change Percent... 113.5% Company........................ Cephalon 2000 Range 52-Wk High.......... 83.63 2000 Range 52-Wk Low........... 29.88 2000 Close..................... 63.31 1999 Close..................... 34.56 2000-1999 Net Change Points.... 28.75 2000-1999 Net Change Percent... 83.2% 1999-1998 Net Change Points.... 25.56 1999-1998 Net Change Percent... 284.0% Company........................ Chiron 2000 Range 52-Wk High.......... 71.03 2000 Range 52-Wk Low........... 33.06 2000 Close..................... 44.50 1999 Close..................... 42.38 2000-1999 Net Change Points.... 2.13 2000-1999 Net Change Percent... 5.0% 1999-1998 Net Change Points.... 16.19 1999-1998 Net Change Percent... 61.8% Company........................ Cor Therap. (1) 2000 Range 52-Wk High.......... 67.25 2000 Range 52-Wk Low........... 11.75 2000 Close..................... 35.19 1999 Close..................... 13.44 2000-1999 Net Change Points.... 21.75 2000-1999 Net Change Percent... 161.8% 1999-1998 Net Change Points.... 6.81 1999-1998 Net Change Percent... 102.7% Footnote....................... (1) stock split 2 for 1. Company........................ Corvas Intl. 2000 Range 52-Wk High.......... 27.88 2000 Range 52-Wk Low........... 4.00 2000 Close..................... 14.38 1999 Close..................... 4.44 2000-1999 Net Change Points.... 9.94 2000-1999 Net Change Percent... 224.1% 1999-1998 Net Change Points.... 1.63 1999-1998 Net Change Percent... 57.9% Company........................ Cytogen 2000 Range 52-Wk High.......... 21.81 2000 Range 52-Wk Low........... 2.00 2000 Close..................... 2.34 1999 Close..................... 2.59 2000-1999 Net Change Points.... -0.25 2000-1999 Net Change Percent... -9.8% 1999-1998 Net Change Points.... 1.75 1999-1998 Net Change Percent... 208.8% Company........................ CV Therapeutics 2000 Range 52-Wk High.......... 93.13 2000 Range 52-Wk Low........... 22.50 2000 Close..................... 70.75 1999 Close..................... 26.06 2000-1999 Net Change Points.... 44.69 2000-1999 Net Change Percent... 171.5% 1999-1998 Net Change Points.... 21.31 1999-1998 Net Change Percent... 448.6% Company........................ Enzon 2000 Range 52-Wk High.......... 84.13 2000 Range 52-Wk Low........... 22.75 2000 Close..................... 62.06 1999 Close..................... 43.38 2000-1999 Net Change Points.... 18.69 2000-1999 Net Change Percent... 43.1% 1999-1998 Net Change Points.... 30.07 1999-1998 Net Change Percent... 225.9% Company........................ Genelabs Tech. 2000 Range 52-Wk High.......... 16.50 2000 Range 52-Wk Low........... 2.72 2000 Close..................... 4.09 1999 Close..................... 5.50 2000-1999 Net Change Points.... -1.41 2000-1999 Net Change Percent... -25.6% 1999-1998 Net Change Points.... 2.75 1999-1998 Net Change Percent... 100.0% Company........................ Genset SA 2000 Range 52-Wk High.......... 78.94 2000 Range 52-Wk Low........... 11.88 2000 Close..................... 12.63 1999 Close..................... 19.06 2000-1999 Net Change Points.... -6.43 2000-1999 Net Change Percent... -33.7% 1999-1998 Net Change Points.... -8.57 1999-1998 Net Change Percent... -31.0% Company........................ Genzyme 2000 Range 52-Wk High.......... 103.75 2000 Range 52-Wk Low........... 39.69 2000 Close..................... 89.94 1999 Close..................... 45.00 2000-1999 Net Change Points.... 44.94 2000-1999 Net Change Percent... 99.9% 1999-1998 Net Change Points.... -4.75 1999-1998 Net Change Percent... -9.5% Company........................ Gilead Sciences 2000 Range 52-Wk High.......... 118.13 2000 Range 52-Wk Low........... 43.25 2000 Close..................... 82.94 1999 Close..................... 54.13 2000-1999 Net Change Points.... 28.82 2000-1999 Net Change Percent... 53.2% 1999-1998 Net Change Points.... 13.07 1999-1998 Net Change Percent... 31.8% Company........................ Human Genome Sc. (1) (a) 2000 Range 52-Wk High.......... 116.38 2000 Range 52-Wk Low........... 25.00 2000 Close..................... 69.31 1999 Close..................... 38.16 2000-1999 Net Change Points.... 31.15 2000-1999 Net Change Percent... 81.6% 1999-1998 Net Change Points.... 29.27 1999-1998 Net Change Percent... 329.2% Footnote....................... (1) stock split 2 for 1. (a) stock split twice - 11/8 and 10/5. Company........................ Icos 2000 Range 52-Wk High.......... 68.00 2000 Range 52-Wk Low........... 26.88 2000 Close..................... 51.94 1999 Close..................... 29.25 2000-1999 Net Change Points.... 22.69 2000-1999 Net Change Percent... 77.6% 1999-1998 Net Change Points.... -0.50 1999-1998 Net Change Percent... -1.7% Company........................ Immune Response 2000 Range 52-Wk High.......... 19.75 2000 Range 52-Wk Low........... 2.48 2000 Close..................... 2.63 1999 Close..................... 4.34 2000-1999 Net Change Points.... -1.71 2000-1999 Net Change Percent... -39.5% 1999-1998 Net Change Points.... -6.54 1999-1998 Net Change Percent... -60.1% Company........................ Immunex (3) 2000 Range 52-Wk High.......... 83.59 2000 Range 52-Wk Low........... 24.19 2000 Close..................... 40.63 1999 Close..................... 36.50 2000-1999 Net Change Points.... 4.13 2000-1999 Net Change Percent... 11.3% 1999-1998 Net Change Points.... 26.02 1999-1998 Net Change Percent... 248.3% Footnote....................... (3) stock split 3 for 1. Company........................ Immunogen 2000 Range 52-Wk High.......... 45.50 2000 Range 52-Wk Low........... 4.50 2000 Close..................... 21.44 1999 Close..................... 5.50 2000-1999 Net Change Points.... 15.94 2000-1999 Net Change Percent... 289.8% 1999-1998 Net Change Points.... 3.31 1999-1998 Net Change Percent... 151.1% Company........................ Incyte Genomics (1) (5) 2000 Range 52-Wk High.......... 144.53 2000 Range 52-Wk Low........... 21.69 2000 Close..................... 24.88 1999 Close..................... 30.00 2000-1999 Net Change Points.... -5.12 2000-1999 Net Change Percent... -17.1% 1999-1998 Net Change Points.... 11.31 1999-1998 Net Change Percent... 60.5% Footnote....................... (1) stock split 2 for 1. (5) name change - formerly Incyte Pharmaceutical. Company........................ Isis Pharm. 2000 Range 52-Wk High.......... 39.00 2000 Range 52-Wk Low........... 5.03 2000 Close..................... 10.63 1999 Close..................... 6.25 2000-1999 Net Change Points.... 4.38 2000-1999 Net Change Percent... 70.1% 1999-1998 Net Change Points.... -6.69 1999-1998 Net Change Percent... -51.7% Company........................ Ligand Pharm. 2000 Range 52-Wk High.......... 26.50 2000 Range 52-Wk Low........... 9.69 2000 Close..................... 14.00 1999 Close..................... 12.88 2000-1999 Net Change Points.... 1.13 2000-1999 Net Change Percent... 8.7% 1999-1998 Net Change Points.... 1.25 1999-1998 Net Change Percent... 10.7% Company........................ MGI Pharma 2000 Range 52-Wk High.......... 54.75 2000 Range 52-Wk Low........... 10.75 2000 Close..................... 16.50 1999 Close..................... 11.94 2000-1999 Net Change Points.... 4.56 2000-1999 Net Change Percent... 38.2% 1999-1998 Net Change Points.... 2.19 1999-1998 Net Change Percent... 22.4% Company........................ Magainin Pharm. 2000 Range 52-Wk High.......... 10.69 2000 Range 52-Wk Low........... 1.28 2000 Close..................... 2.22 1999 Close..................... 1.81 2000-1999 Net Change Points.... 0.41 2000-1999 Net Change Percent... 22.5% 1999-1998 Net Change Points.... -1.38 1999-1998 Net Change Percent... -43.2% Company........................ Matrix Pharm. 2000 Range 52-Wk High.......... 22.06 2000 Range 52-Wk Low........... 4.31 2000 Close..................... 17.13 1999 Close..................... 4.75 2000-1999 Net Change Points.... 12.38 2000-1999 Net Change Percent... 260.6% 1999-1998 Net Change Points.... 2.12 1999-1998 Net Change Percent... 80.6% Company........................ Medimmune (3) 2000 Range 52-Wk High.......... 86.13 2000 Range 52-Wk Low........... 41.98 2000 Close..................... 47.69 1999 Close..................... 55.29 2000-1999 Net Change Points.... -7.60 2000-1999 Net Change Percent... -13.7% 1999-1998 Net Change Points.... 38.72 1999-1998 Net Change Percent... 233.7% Footnote....................... (3) stock split 3 for 1. Company........................ NABI 2000 Range 52-Wk High.......... 12.00 2000 Range 52-Wk Low........... 2.50 2000 Close..................... 4.63 1999 Close..................... 4.63 2000-1999 Net Change Points.... 0.00 2000-1999 Net Change Percent... 0% 1999-1998 Net Change Points.... 1.94 1999-1998 Net Change Percent... 71.9% Company........................ Protein Design Labs (1) 2000 Range 52-Wk High.......... 169.00 2000 Range 52-Wk Low........... 25.91 2000 Close..................... 86.88 1999 Close..................... 35.00 2000-1999 Net Change Points.... 51.88 2000-1999 Net Change Percent... 148.2% 1999-1998 Net Change Points.... 23.44 1999-1998 Net Change Percent... 202.8% Footnote....................... (1) stock split 2 for 1. Company........................ Regeneron 2000 Range 52-Wk High.......... 57.38 2000 Range 52-Wk Low........... 10.13 2000 Close..................... 35.27 1999 Close..................... 12.75 2000-1999 Net Change Points.... 22.52 2000-1999 Net Change Percent... 176.6% 1999-1998 Net Change Points.... 5.37 1999-1998 Net Change Percent... 72.8% Company........................ Repligen 2000 Range 52-Wk High.......... 18.00 2000 Range 52-Wk Low........... 2.88 2000 Close..................... 3.38 1999 Close..................... 3.13 2000-1999 Net Change Points.... 0.26 2000-1999 Net Change Percent... 8.2% 1999-1998 Net Change Points.... 1.85 1999-1998 Net Change Percent... 144.1% Company........................ Scios 2000 Range 52-Wk High.......... 24.63 2000 Range 52-Wk Low........... 3.38 2000 Close..................... 23.06 1999 Close..................... 4.19 2000-1999 Net Change Points.... 18.87 2000-1999 Net Change Percent... 450.7% 1999-1998 Net Change Points.... -6.19 1999-1998 Net Change Percent... -59.7% Company........................ Sicor 2000 Range 52-Wk High.......... 17.00 2000 Range 52-Wk Low........... 6.25 2000 Close..................... 14.44 1999 Close..................... 7.75 2000-1999 Net Change Points.... 6.69 2000-1999 Net Change Percent... 86.3% 1999-1998 Net Change Points.... 3.22 1999-1998 Net Change Percent... 71.1% Company........................ Sepracor (1) 2000 Range 52-Wk High.......... 140.00 2000 Range 52-Wk Low........... 45.06 2000 Close..................... 80.13 1999 Close..................... 49.59 2000-1999 Net Change Points.... 30.54 2000-1999 Net Change Percent... 61.6% 1999-1998 Net Change Points.... 5.53 1999-1998 Net Change Percent... 12.6% Footnote....................... (1) stock split 2 for 1. Company........................ SkyePharma 2000 Range 52-Wk High.......... 30.50 2000 Range 52-Wk Low........... 7.38 2000 Close..................... 9.06 1999 Close..................... 7.38 2000-1999 Net Change Points.... 1.68 2000-1999 Net Change Percent... 22.8% 1999-1998 Net Change Points.... -5.12 1999-1998 Net Change Percent... -41.0% Company........................ StemCell (4) 2000 Range 52-Wk High.......... 20.00 2000 Range 52-Wk Low........... 1.31 2000 Close..................... 2.50 1999 Close..................... 1.47 2000-1999 Net Change Points.... 1.03 2000-1999 Net Change Percent... 70.1% 1999-1998 Net Change Points.... 0.00 1999-1998 Net Change Percent... .0% Footnote....................... (4) name change - formerly CytoTherapeutics. Company........................ Teva Pharm. (1) 2000 Range 52-Wk High.......... 78.75 2000 Range 52-Wk Low........... 31.94 2000 Close..................... 73.25 1999 Close..................... 35.84 2000-1999 Net Change Points.... 37.41 2000-1999 Net Change Percent... 104.4% 1999-1998 Net Change Points.... 15.50 1999-1998 Net Change Percent... 76.2% Footnote....................... (1) stock split 2 for 1. Company........................ Transkaryotic Therapies 2000 Range 52-Wk High.......... 87.00 2000 Range 52-Wk Low........... 22.50 2000 Close..................... 36.44 1999 Close..................... 38.50 2000-1999 Net Change Points.... -2.06 2000-1999 Net Change Percent... -5.4% 1999-1998 Net Change Points.... 13.12 1999-1998 Net Change Percent... 51.7% Company........................ Triangle Pharm. 2000 Range 52-Wk High.......... 27.25 2000 Range 52-Wk Low........... 4.50 2000 Close..................... 4.94 1999 Close..................... 12.81 2000-1999 Net Change Points.... -7.87 2000-1999 Net Change Percent... -61.4% 1999-1998 Net Change Points.... -0.82 1999-1998 Net Change Percent... -6.0% Company........................ VaxGen 2000 Range 52-Wk High.......... 36.88 2000 Range 52-Wk Low........... 11.63 2000 Close..................... 19.50 1999 Close..................... 18.50 2000-1999 Net Change Points.... 1.00 2000-1999 Net Change Percent... 5.4% 1999-1998 Net Change Points.... - - 1999-1998 Net Change Percent... - - Company........................ Vertex Pharm. (1) 2000 Range 52-Wk High.......... 99.25 2000 Range 52-Wk Low........... 16.50 2000 Close..................... 71.50 1999 Close..................... 17.50 2000-1999 Net Change Points.... 54.00 2000-1999 Net Change Percent... 308.6% 1999-1998 Net Change Points.... 2.62 1999-1998 Net Change Percent... 17.6% Footnote....................... (1) stock split 2 for 1. Company........................ Vical 2000 Range 52-Wk High.......... 73.50 2000 Range 52-Wk Low........... 13.00 2000 Close..................... 18.50 1999 Close..................... 29.94 2000-1999 Net Change Points.... -11.44 2000-1999 Net Change Percent... -38.2% 1999-1998 Net Change Points.... 15.75 1999-1998 Net Change Percent... 111.0% Company........................ Xoma 2000 Range 52-Wk High.......... 16.00 2000 Range 52-Wk Low........... 2.75 2000 Close..................... 9.75 1999 Close..................... 3.00 2000-1999 Net Change Points.... 6.75 2000-1999 Net Change Percent... 225.0% 1999-1998 Net Change Points.... -0.19 1999-1998 Net Change Percent... -6.0% Company........................ F-D-C Index 2000 Range 52-Wk High.......... 3030.9 2000 Range 52-Wk Low........... 7830.0 2000 Close..................... 4765.6 1999 Close..................... 4164.8 2000-1999 Net Change Points.... 2000-1999 Net Change Percent... 14.4 1999-1998 Net Change Points.... 1999-1998 Net Change Percent... 105.5 Services Company........................ Advance Paradigm 2000 Range 52-Wk High.......... 51.63 2000 Range 52-Wk Low........... 9.50 2000 Close..................... 45.50 1999 Close..................... 21.56 2000-1999 Net Change Points.... 23.94 2000-1999 Net Change Percent... 111.0% 1999-1998 Net Change Points.... 4.06 1999-1998 Net Change Percent... 23.2% Company........................ Baron LePore 2000 Range 52-Wk High.......... 12.44 2000 Range 52-Wk Low........... 5.88 2000 Close..................... 10.50 1999 Close..................... 6.50 2000-1999 Net Change Points.... 4.00 2000-1999 Net Change Percent... 61.5% 1999-1998 Net Change Points.... -28.00 1999-1998 Net Change Percent... -81.2% Company........................ Chronimed 2000 Range 52-Wk High.......... 11.00 2000 Range 52-Wk Low........... 4.94 2000 Close..................... 12.13 1999 Close..................... 7.69 2000-1999 Net Change Points.... 4.44 2000-1999 Net Change Percent... 57.7% 1999-1998 Net Change Points.... -5.25 1999-1998 Net Change Percent... -40.6% Company........................ Clintrials Research 2000 Range 52-Wk High.......... 5.75 2000 Range 52-Wk Low........... 2.28 2000 Close..................... 5.19 1999 Close..................... 4.13 2000-1999 Net Change Points.... 1.06 2000-1999 Net Change Percent... 25.7% 1999-1998 Net Change Points.... 0.19 1999-1998 Net Change Percent... 4.8% Company........................ Drugstore.com 2000 Range 52-Wk High.......... 39.38 2000 Range 52-Wk Low........... 0.78 2000 Close..................... 0.91 1999 Close..................... 36.19 2000-1999 Net Change Points.... -35.28 2000-1999 Net Change Percent... -97.5% 1999-1998 Net Change Points.... - - 1999-1998 Net Change Percent... - - Company........................ Express Scripts 2000 Range 52-Wk High.......... 105.50 2000 Range 52-Wk Low........... 28.50 2000 Close..................... 102.25 1999 Close..................... 64.00 2000-1999 Net Change Points.... 38.25 2000-1999 Net Change Percent... 59.8% 1999-1998 Net Change Points.... -3.13 1999-1998 Net Change Percent... -4.7% Company........................ Ilex Oncology 2000 Range 52-Wk High.......... 54.13 2000 Range 52-Wk Low........... 15.91 2000 Close..................... 26.31 1999 Close..................... 24.13 2000-1999 Net Change Points.... 2.18 2000-1999 Net Change Percent... 9.0% 1999-1998 Net Change Points.... 13.00 1999-1998 Net Change Percent... 116.8% Company........................ Parexel Intl. 2000 Range 52-Wk High.......... 15.44 2000 Range 52-Wk Low........... 8.06 2000 Close..................... 10.81 1999 Close..................... 11.81 2000-1999 Net Change Points.... -1.00 2000-1999 Net Change Percent... -8.5% 1999-1998 Net Change Points.... -13.19 1999-1998 Net Change Percent... -52.8% Company........................ PlanetRx.com 2000 Range 52-Wk High.......... 154.00 2000 Range 52-Wk Low........... 0.22 2000 Close..................... 0.28 1999 Close..................... 14.05 2000-1999 Net Change Points.... -14.22 2000-1999 Net Change Percent... -98.1% 1999-1998 Net Change Points.... - - 1999-1998 Net Change Percent... - - Company........................ Professional Detailing 2000 Range 52-Wk High.......... 142.00 2000 Range 52-Wk Low........... 18.00 2000 Close..................... 105.77 1999 Close..................... 29.94 2000-1999 Net Change Points.... 75.83 2000-1999 Net Change Percent... 253.3% 1999-1998 Net Change Points.... 1.69 1999-1998 Net Change Percent... 6.0% Company........................ Quintiles Transnational 2000 Range 52-Wk High.......... 35.00 2000 Range 52-Wk Low........... 12.00 2000 Close..................... 20.94 1999 Close..................... 18.69 2000-1999 Net Change Points.... 2.25 2000-1999 Net Change Percent... 12.0% 1999-1998 Net Change Points.... -34.69 1999-1998 Net Change Percent... -65.0% Company........................ Ventiv Health 2000 Range 52-Wk High.......... 15.00 2000 Range 52-Wk Low........... 7.44 2000 Close..................... 12.56 1999 Close..................... 9.19 2000-1999 Net Change Points.... 3.37 2000-1999 Net Change Percent... 36.7% 1999-1998 Net Change Points.... - - 1999-1998 Net Change Percent... - - Company........................ F-D-C Index 2000 Range 52-Wk High.......... 4265.0 2000 Range 52-Wk Low........... 978.4 2000 Close..................... 2642.0 1999 Close..................... 2521.5 2000-1999 Net Change Points.... 2000-1999 Net Change Percent... 4.8 1999-1998 Net Change Points.... 1999-1998 Net Change Percent... 23.9 Company........................ Composite 2000 Range 52-Wk High.......... 8048.2 2000 Range 52-Wk Low........... 3048.1 2000 Close..................... 4903.1 1999 Close..................... 4313.1 2000-1999 Net Change Points.... 2000-1999 Net Change Percent... 13.7 1999-1998 Net Change Points.... 1999-1998 Net Change Percent... 98.4 </pre> <br /> <br />