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TLC Evacet Cardiotoxicity Advantage Does Not Outweigh Unclear Efficacy

Executive Summary

The Liposome Company's Evacet (liposomal doxorubicin, TLC D-99) has a cardiotoxicity advantage over conventional doxorubicin when used first-line for metastatic breast cancer, the Oncologic Drugs Advisory Committee agreed Sept. 16.

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FDA Urgency To Clear TLC Evacet May Be Lessened By Ellence Approval

The impetus for FDA to approve The Liposome Company's Evacet (liposomal doxorubicin, D-99), based on incomplete efficacy data may be lessened by the recent U.S. approval of Pharmacia & Upjohn's Ellence (epirubicin).

Part D Discount Liability Coming Into Focus: CMS Releases Drug Cost Data

Newly released Medicare Part D data sheds light on the sales hit that branded pharmaceutical manufacturers will face when the coverage gap discount program gets under way in 2011




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