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Neurogen/Pfizer to collaborate on anti-obesity drug under agreement potentially worth over $60 mil.

Executive Summary

NEUROGEN AND PFIZER WILL COLLABORATE IN ANTI-OBESITY DRUG DEVELOPMENT under an agreement in principle announced Nov. 6. Neurogen said the agreement, its third collaboration with Pfizer, "can mean as much as $60 mil." to the company, plus income from profit-sharing, manufacturing options and royalties. Pfizer will have worldwide rights to Neurogen's neuropeptide Y1 antagonist, NGD 95-1, which might suppress appetite by blocking the action of NPY, which has shown evidence of being a potent eating stimulator, the company said.

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