Acetaminophen preferred first-line osteoarthritis therapy for hip/knee pain -- ACR guidelines.
ACETAMINOPHEN PREFERRED OSTEOARTHRITIS FIRST-LINE DRUG THERAPY for pain in the hip and knee in doses up to 1,000 mg, four times a day, according to American College of Rheumatology guidelines for osteoarthritis management released Oct. 23. If responses to acetaminophen therapy are inadequate, nonsteroidal anti-inflammatory drug therapy is the next step in the treatment continuum.
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