Pink Sheet is part of Pharma Intelligence UK Limited

This site is operated by Pharma Intelligence UK Limited, a company registered in England and Wales with company number 13787459 whose registered office is 5 Howick Place, London SW1P 1WG. The Pharma Intelligence group is owned by Caerus Topco S.à r.l. and all copyright resides with the group.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction

J&J/BRITISH BIO-TECHNOLOGY "SECOND-GENERATION" ANTI-CHOLESTEROL DRUG

Executive Summary

J&J/BRITISH BIO-TECHNOLOGY "SECOND-GENERATION" ANTI-CHOLESTEROL DRUG will be marketed in the U.S. and elsewhere outside the U.K. by Johnson & Johnson under a "long term" R&D agreement announced July 19. British Bio-technology Ltd. will retain rights in the U.K. The agreement involves joint development of new chemicals produced by British Bio-technology's research on second generation synthetic HGM-CoA reductase inhibitors. The agreement calls for British Bio-technology to conduct the "discovery" phases of the research, including chemical synthesis and pharmacological testing. J&J subsidiary McNeil Pharmaceutical will handle preclinical toxicology and clinical testing for international registration. Financial details of the agreement were not disclosed. J&J said the anticholesterol drug R&D agreement is the first research collaboration announced between the two firms. Earlier this year, J&J completed an $ 1.8 mil. equity investment in British Bio-technology, acquairing 500,000 shares, which represents a 5.7% interest in the Oxford, England-based biotech company. Announcing the contract, British Bio-technology CEO Keith McCullagh said that "the planned program combines British Bio-technology's highly competitive medicinal chemistry with pharmacological research in the cholesterol-lowering field with Johnson & Johnson's international marketing strengths." McNeil President Thomas Odiorne added: "We're very pleased to have the opportunity to broaden our research base as part of our continuing search for promising new drugs to treat cardiovascular disease." SmithKline, which also holds a 5.7% position in British Bio-technology, currently has agreements with the company for the marketing of British Bio-technology's Designer Genes synthetic genes and for research and development of second generation thrombolytic agents. SmithKline recently discontinued thrombolytic R&D programs with Biogen and Damon Biotech in the U.S., but decided to stick with British Bio-technology. The U.K. biotech firm also recently announced research collaborations with Pfizer, in the area of vascular biology and endothelial research, and with Abbott, for diagnostics products.

You may also be interested in...



Part D Discount Liability Coming Into Focus: CMS Releases Drug Cost Data

Newly released Medicare Part D data sheds light on the sales hit that branded pharmaceutical manufacturers will face when the coverage gap discount program gets under way in 2011

FDA Skin Infections Guidance Spurs Debate On Endpoint Relevance

FDA appears headed for a showdown with clinicians and the pharmaceutical industry over the proposed new clinical trial endpoints for acute bacterial skin and skin structure infections, the guidance's approach for justifying a non-inferiority margin and proposed changes in the types of patients that should be enrolled in trials

Shire Hopes To Sow Future Deals With $50M Venture Fund

Specialty drug maker Shire has quietly begun scouting deals with a brand-new $50 million venture fund, the latest of several in-house investment arms to launch with their parent company's pipelines, not profits, as the measure of their worth

Latest Headlines
See All
UsernamePublicRestriction

Register

PS014017

Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel