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Alzheimer's disease drug

Executive Summary

Sen. Pell (D-R.I.) introduced legislation to require the National Institute on Aging to provide $2 mil. per year for a three-year study of tacrine (tetrahydroaminoacridine or THA) for treatment of senile dementia. Warner-Lambert has expressed interest in developing the cholinergic agent, which was first marketed in the 1930s. The Senate Labor & Human Resources Committee member noted that tacrine achieved a 92% success rate in a private study conducted in 19 patients and published last fall in the New England Journal of Medicine.

Sen. Pell (D-R.I.) introduced legislation to require the National Institute on Aging to provide $2 mil. per year for a three-year study of tacrine (tetrahydroaminoacridine or THA) for treatment of senile dementia. Warner-Lambert has expressed interest in developing the cholinergic agent, which was first marketed in the 1930s. The Senate Labor & Human Resources Committee member noted that tacrine achieved a 92% success rate in a private study conducted in 19 patients and published last fall in the New England Journal of Medicine.

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