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Roche’s Kadcyla Fails To Better Herceptin In First-Line Breast Cancer

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Sales estimates for Roche’s Kadcyla will be cut sharply after news the MARIANNE study didn’t show the antibody-drug conjugate performing better than Herceptin in treating first-line breast cancer. Firm’s early Alzheimer’s therapy gantenerumab also fails in Phase III.

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