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GSK Overall Survival Data Clinches Role For BRAF/MEK Combo In Melanoma

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

In the COMBI-v study, BRAF/MEK combination Tafinlar/Mekinist improves overall survival by 31% compared to BRAF monotherapy. GSK’s combination and Genentech’s cobimetinib/Zelboraf combination both improve progression-free survival and reduce cutaneous malignancies compared to monotherapy.


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