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Bristol’s Phase III Opdivo Data Clarify PD-1’s Place In Melanoma

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

In the first randomized Phase III results for a PD-1 inhibitor to be presented at a major medical meeting, Bristol reports a 32% response rate for nivolumab compared to 11% for investigator’s choice of therapy in relapsed melanoma. Bristol immunotherapy exec Michael Giordano says the jury’s still out on PD-L1 as a predictive biomarker.


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