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Celgene Pulls Back From First-Line CLL As Revlimid ORIGIN Trial Terminates

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Imbalance of deaths for Revlimid in the ORIGIN treatment-naïve CLL study could be due to the advanced age of participants or their many comorbidities. Future of drug as monotherapy in treatment-naïve patients is now unlikely, but studies in later lines of treatment go on.

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