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Biogen/Elan Seek First-Line Claim For Tysabri In JCV-Negative MS Patients

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Given the risks of progressive multifocal leukoencephalopathy, a proposed restriction appears aimed at blunting the potentially unfavorable impact that longer duration of use in the first-line setting would have on natalizumab’s risk/benefit profile.

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