Rigel R&D Strategy Emphasizes Early Pipeline, Led By Asthma Drug
This article was originally published in Pharmaceutical Approvals Monthly
Executive Summary
Rigel’s focus on its early-stage projects for serious unmet medical needs overshadowed its Phase III rheumatoid arthritis candidate with AstraZeneca.
You may also be interested in...
With Much Riding On Fostamatinib, Rigel Awaits The Phase III Results
Dependent on revenues from AstraZeneca-partnered fostamatinib to fund its growth, Rigel has built a diverse and innovative portfolio. But disappointing results from a Phase IIb dose-ranging trial of fostamatinib – three other pivotal trials will report out soon – could signal trouble for the biopharma. Rigel execs Jim Gower and Raul Rodriguez share perspectives on the AstraZeneca deal and fostamatinib’s prospects.
Roche Believes Biomarker Could Position Antibody For Severe Asthma For Success
During an investor presentation Nov. 7, the Swiss pharma outlined its plans to move lebrikizumab into Phase III next year.
Tofacitinib Data Is In: As Effective As Humira, But Safety Remains A Question
Pfizer Inc. on Sept. 8 released some data from three previously undisclosed pivotal trials for tofacitinib, its high-profile, first-in-class JAK3 inhibitor for rheumatoid arthritis, which it says shows that the drug is equal in efficacy to Abbott Laboratory Inc.’s bestselling TNF inhibitor Humira.