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Bristol/Pfizer's Apixaban Bests Lovenox At Preventing VTE In Second Attempt

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

With the positive results of the ADVANCE II study of Bristol-Myers Squibb/Pfizer's apixaban now offsetting the failed non-inferiority of the earlier ADVANCE I study, the ADVANCE III study is shaping up to be the tie-breaker for how the investigational anticoagulant stacks up against Sanofi-Aventis' low molecular weight heparin Lovenox (enoxaparin) in patients undergoing orthopedic surgery
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