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Does Xenazine's Effect On Chorea Outweigh Risks? Ask The Patients

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Including patient-reported outcomes in the pivotal Xenazine trials could have provided valuable insight into the "net benefit" of the drug as FDA struggled to weigh the difficult combination of positive effects on one major symptom of Huntington’s disease and potential negative effects on other symptoms, FDA review documents suggest.

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