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AstraZeneca Recentin To Start Phase III For Colorectal Cancer, But Not NSCLC

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Phase II non-small cell lung cancer data on cediranib did not meet criteria for Phase III, and showed imbalance in toxicity

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AstraZeneca Eliminates Advanced Colorectal Cancer Claim For Recentin

AstraZeneca will no longer file marketing applications in the U.S. and Europe this fall for Recentin (cediranib) in first-line metastatic colorectal cancer after the oral VEGF inhibitor failed to show an overall survival benefit in the Phase III HORIZON II study, the company announced May 28

AstraZeneca Eliminates Advanced Colorectal Cancer Claim For Recentin

AstraZeneca will no longer file marketing applications in the U.S. and Europe this fall for Recentin (cediranib) in first-line metastatic colorectal cancer after the oral VEGF inhibitor failed to show an overall survival benefit in the Phase III HORIZON II study, the company announced May 28

Another One Down: AstraZeneca Eliminates Advanced Colorectal Cancer Claim For Recentin

Continued development of the VEGF inhibitor depends on results from studies in recurring glioblastoma.

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