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Cytokinetics takes on more ispinesib duties

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Cytokinetics and GlaxoSmithKline have amended their agreement relating to development of Cytokinetics' kinase spindle protein inhibitors, including the Phase II oncologic ispinesib, Cytokinetics says Nov. 27. The San Francisco biotech plans "a focused development program for ispinesib" that builds on GSK's Phase I/II efforts with the compound. During a second quarter earnings call, CEO James Sabry said the firm would cast a wider net of trials in the wake of ispinesib's Phase II failure in lung cancer (1Pharmaceutical Approvals Monthly August 2006, p. 6)...

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