Pink Sheet is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

Merck Zostavax data

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Merck's shingles vaccine Zostavax (herpes zoster vaccine live (Oka/Merck)) reduced both total pain burden and postherpetic neuralgia by more than 60%, according to a 38,500-patient study published in the June 2 New England Journal of Medicine. The Phase III Shingles Prevention Study showed that the vaccine reduced total burden of pain and discomfort by 61.1% and postherpetic neuralgia by 66.5% (p<0.001). Overall shingles incidence was also significantly reduced, by 51.3%. Merck submitted a Zostavax BLA to FDA April 25 but has not yet been notified regarding a priority review designation (1Pharmaceutical Approvals Monthly May 2005, In Brief)...

You may also be interested in...



Merck Zostavax BLA

Merck submits BLA April 25 for its herpes zoster vaccine Zostavax. The firm is seeking claims for prevention of herpes zoster (shingles); prevention of postherpetic neuralgia, the most common complication of shingles; and reduction of acute and chronic shingles-associated pain in adults. The firm estimates that up to 800,000 people in the U.S. suffer from shingles each year. Merck plans to submit another vaccine this year: the human papilloma virus vaccine Gardasil is slated for submission in the second half of the year (1Pharmaceutical Approvals Monthly April 2005, In Brief)...

Quick Listen: Scrip’s Five Must-Know Things

Join us for an audio catch-up on the latest key developments in the global biopharma industry, as reported by 

Prop 65 Warnings Intended For Small Spaces But Used On Luggage? California Proposes Limits

California proposes limiting short-form Prop 65 warnings to products with 5 inches or less of labeling space, while prohibiting their use in online and catalog warnings. The number of products with the warnings, used even on vacuum cleaners, luggage and guitars, has made tracking them impossible.

Topics

UsernamePublicRestriction

Register

OM006922

Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel