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Schering Noxafil Phase III

This article was originally published in Pharmaceutical Approvals Monthly

Executive Summary

Schering-Plough's triazole antifungal Noxafil (posaconazole oral suspension) shows significantly better results than standard antifungals in a study presented Dec. 8 at the American Society of Hematology meeting. Overall success rate was 42% in patients receiving Noxafil 800 mg/day for up to one year, vs. 26% for standard therapy (p=0.006). Noxafil is one of three launches Schering is anticipating by 2007; the firm also expects to introduce the oncologic Sarasar (lonafarnib) and a fixed combination of Zetia and Zocor, which is pending at FDA with a July user fee goal...
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