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Start-Up Previews (12/2009)

Executive Summary

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, "Bringing New Blood to the Anemia Market," features profiles of Akebia, Neumedicines and Palkion. Plus these Start-Ups Across Health Care: Aterovax, Pico-Tesla Magnetic Therapies, SpineAlign Medical, Theraclion, Virdante Pharmaceuticals and Zacharon Pharmaceuticals.

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Theraclion SAS

Paris-based Theraclion SAS has developed a non-surgical approach to treating hyperparathyroidism. The company's TH-One technology employs an externally applied converging beam of high-intensity focused ultrasound to create a rapid temperature rise in the extremely small parathyroid glands. Each pulse of energy produces a small lesion of coagulation, leading to destruction of the parathyroids.

Pico-Tesla Magnetic Therapies LLC

Pico-Tesla Magnetic Therapies LLC's [noninvasive neuromodulation platform uses low levels of electromagnetic field to improve signs and symptoms of Parkinson's disease. The field strengths used by the company's Resonator device are in orders of magnitude below those utilized in MRI scanners or transcranial magnetic stimulators and thus should present no risk to patients.

SpineAlign Medical Inc.

Patients with osteoporotic vertebral compression fractures now have another alternative to vertebroplasty or kyphoplasty. The SpineAlign system from SpineAlign Medical Inc. uses a combination of cement and a permanent implant to elevate the vertebral endplates in parallel. In addition, the expandable metal device is composed of nitinol threaded at the end, so that a pedicle screw can be attached and locked into the system for a sturdy construct.

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